No, but with a caveat. If you are talking about a system crossing a large mountain range, such as the Rockies, then you can see surface low pressure systems form (these are often called 'Colorado lows') as the vorticity (spin) associated with the mid/upper level feature is stretched vertically, potentially leading to a spin-up at the surface.

In the most general of cases, however, particularly for a feature in the tropics, mountains are not conducive to development of any surface feature, regardless of whether or not there is an upper low present.

Ryan -- way too early to tell, and I'm not even sure which feature you're looking at... The pattern doesn't favor anything coming from the south and getting that far north right now with any semblance of organization.