Looks like the only city in Nicaragua which will be directly affected is Puerto Cabezas and even this one will be on the left hand side of Felix. In Honduras the closest city would be Puerto Lempira, which should not get CAT5 winds. So maybe this one will not cause too much damage along the coast and will weaken enough by the time it reaches the most populated areas. I suppose that the biggest risk from Felix would be rain in the mountainous areas, right?

Judging from the map I have, there are only two roads into Puerto Cabezas. There is an airport, but it looks small and will probably take a bad beating. So getting help there will be done helicopters (of which Nicaragua has about 50 usable for transporting rescue teams, engineers, supplies). Hopefully, the authorities will be able to heliport equipment and troops to open the airport.